Lions vs Rams Predictions: Quick Facts
The table below quickly highlights the most important facts related to odds for this Week 15 matchup.
| â Favorite | Rams |
| âď¸ Lions Win | 32.3% Chance |
| đ˘ Point Spread | DET +6 |
| đ Moneyline | DET +210 |
| đ Game Total | o/u 55.5 |
| â Last Verified | December 8, 2025 |
In addition to the odds-related quick facts, we also have the expected lineups, the weather forecast, location details, relevant statistics and injuries for the game, which is critical info to consider alongside the betting lines.
In addition to the odds-related quick facts, we also have the expected lineups, the weather forecast, location details, relevant statistics and injuries for the game, which is critical info to consider alongside the betting lines.
In addition to the odds-related quick facts, we also have the expected lineups, the weather forecast, location details, relevant statistics and injuries for the game, which is critical info to consider alongside the betting lines.
Who is Favored to Win?
The Rams are favored to beat the Lions in Week 15 of the 2025-26 season. Comparing multiple betting markets across sportsbooks like FanDuel, DraftKings, and BetMGM reveals the Lions are the unanimous favorite against the Rams following the initial release of the NFL schedule.
What is the Spread?
The point spread for Lions vs Rams is DET +6 points, which means Los Angeles is expected to win by six or more points.
Breaking Down Moneylines
The moneyline for Lions vs Rams is set at DET +170 and LAR -205, according to DraftKings. This means that the Lions have a 32.3% chance of winning this game, while the Rams have a 71.4% chance.
Game Total: Over/Under
The game total for Lions vs. Rams is set at over/under 55.5 points, according to DraftKings. This means that oddsmakers project plenty of scoring, suggesting confidence in both teamsâ ability to move the ball and capitalize on their offensive strengths.
Related Lions Betting Content:
Detroit Lions Chances to Win vs LA Rams
The Lions have a 32.3% chance to beat the Rams in Week 15, according to the implied probability of their current odds. That number reflects both the Ramsâ recent form and the challenges Detroit faces on the road against a high-powered offense.
How Detroit Wins vs LA
What will it take for the Lions to beat the Rams in Week 15?
- Contain Kyren Williams
- Establish the Run Early
- Force Matt Stafford into making mistakes
First, Detroit will need to contain RB Kyren Williams, who has proven that he could run all day if the Rams were to give him the football. Keeping him in check early will force Los Angeles into more predictable passing situations and limit their ability to control the tempo. Detroitâs front seven must stay disciplined, fill gaps, and avoid the missed tackles that Williams thrives on exploiting.
The Lions need to look at what the Carolina Panthers did to beat the Rams, and replicate the playbook. After setting a record for most passes without an interception, Matt Stafford was picked off twice by the Panthers. Applying similar pressure and disguising coverages could disrupt Staffordâs rhythm and create the same opportunities for turnovers.
Other Notable Lions Matchups:
How LA Wins vs Detroit
How the Rams can win.
- Scoring Early
- Attacking Detroit's Weaknesses
Everyone knows about Williams. But the Rams have also had success through the air, with Stafford connecting with Puca Nacua between the hashmarks and finishing drives with touchdown passes to Davante Adams. If the Lions fail to cover these short and intermediate routes effectively, the Rams could pick up chunk yardage and sustain long drives, keeping Detroitâs offense off the field.
The Rams also must replicate what the Packers did and apply pressure on Jared Goff. This will force him into making mistakes while also disrupting the running game. Consistent pressure up front and well-timed blitzes could create turnovers or negative plays, swinging momentum in Los Angelesâ favor early.
How to Bet on the Game
If you are in Michigan and want to bet on Lions vs Rams, you have an array of options. You can bet online by downloading a betting app like FanDuel, DraftKings or BetMGM, all of which are available in the state and have odds live for this Week 15 showdown. You can also bet in-person at the many brick-and-mortar sportsbooks in the state, including MGM Grand Detroit or MotorCity Casino Hotel.
Exclusive Promos for Betting on the Game
I went through every sports betting app in Michigan to find all the exclusive sportsbook promos available for the Lions Week 15 matchup and listed them below. I've personally used all of these promotions, so I highly recommend capitalizing on each and every one if you're going to bet on the Lions.
How to Watch the Game
The channel to watch the Lions vs Rams Week 15 matchup will be Fox Sports, and it will be at 4:25 PM Eastern Time/1:25 PM Pacific Time.
History of Lions vs Rams
The Lions and Rams have a rich history dating back to the Rams time in Cleveland throughout the 30s and 40s. The team has faced off dozens of time throughout the past century with the Rams holding a slight advantage head-to-head against the Lions.
Record All-Time
- Games Played = 89
- Rams Wins = 45
- Lions Wins = 43
- Ties = 1
- Playoff Matchups = 2
- Super Bowl Matchups = 0
- First Matchup = 1937
- Last Matchup = 2024
The Detroit Lions have faced off against the Cleveland/Los Angeles/St. Louis Rams 88 times total. The Rams have won 45 games, while the Lions have won 42 games. The teams have tied once, back in 1964.
The two franchises have faced off twice in the playoffs if you count the 1952 National Conference championship. The other playoff matchup was just last year in the NFC Wild Card Game.
The first game played between these two franchises was on November 10, 1937, but, back then, the Rams were in Cleveland. Detroit played 15 times before the Rams moved to LA (the first time).
Last 5 Times They Played Each Other
| DATE | MATCHUP | WINNER |
| 09/08/2024 | LAR @ DET | Lions (26-20 OT) |
| 01/14/2024 | LAR @ DET* | Lions (23-24) |
| 10/24/2021 | DET @ LAR | Rams (19-28) |
| 12/02/2018 | LAR @ DET | Rams (30-16) |
| 10/16/2016 | LAR @ DET | Lions (28-31) |
| 12/13/2015 | DET @ STL | Rams (14-21) |
* = playoff game
Last 5 Games They Played This Year
FAQs
The Rams are currently the favorites in this game. Oddsmakers have given them the nod, with the line being at six points. Before the season began, the Lions were the favorites, but that changed as the season progressed, and the Rams continued to play well.
The game total for Lions vs Rams has moved to over/under 55.5 points. The market initially opened at 52.5 points across most betting apps, but has moved to 55.5 points recently. When the teams played in 2024, the Lions won 26-20 in overtime.
If you are in Michigan, you can bet on the Lions vs the Rams in person and online. You can visit one of many physical sportsbooks around the state or download one of the many betting apps., and it will give you numerous options to place a bet.
The Lions will next play the Rams in Week 15, with the game airing live on Fox Sports from SoFi Stadium in Los Angeles. Kickoff is set for 4:25 PM ET, and fans can expect a high-stakes matchup between two NFC contenders.
The keys to the Lions beating the Rams last time they played were they got out to an early lead, they were not passive on offense once they were up and, on Defense, their stout rush defense forced LA to abandon the ground game early.
Author
Brandon Justice is a Writer, Commercial Editor, and Fact Checker for BetMichigan.com. He also writes about the Michigan Wolverines & Detroit Lions, two teams he spent seven years covering professionally. Additionally, the Metro Detroit, Michigan native has covered numerous sports betting perspectives, including everything from analysis & daily picks to reviews & guides.
