Monday Night Football Odds Week 17: Rams @ Falcons
| MNF Odds: Week 17 | Spread | Moneyline | Total |
| Los Angeles Rams | -7.5 | -470 | O 49.5 |
| Indianapolis Colts | +7.5 | +360 | U 49.5 |
The Los Angeles Rams head into Monday Night Football needing a response after a frustrating loss to the Seahawks stalled their momentum in the NFC playoff race. With the postseason picture tightening, this is a must-win for Sean McVayâs group as they look to bounce back, clean up mistakes, and keep their playoff hopes firmly alive.
The Atlanta Falcons are simply playing out the stretch in another lost season, using the final weeks to evaluate talent and play for pride. While Atlanta would love to play spoiler on a national stage, the urgency clearly belongs to the Rams, who canât afford to let this one slip under the bright Monday night lights.
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MNF Betting Odds: 2025 Schedule Breakdown
It's another exciting slate of Monday Night Football games this season, with no game having a spread of greater than 8 points.
There are a lot of good matchups for Monday Night Football this season, including Aaron Rodgers and Josh Allen squaring off in Week 6, in a rematch of the fateful Week 1 MNF games from last season.
| Week | Matchup | Line | TV Network/Results |
|---|---|---|---|
| 1 | Minnesota Vikings vs. Chicago Bears | Vikings +1.5 O/U 43.5 | Vikings win 27-24 |
| 2 | Tampa Bay Buccaneers vs. Houston Texans | Texans -1.5 O/U 46.5 | Bucs win 20-19 |
| 2 | Los Angeles Chargers vs. Las Vegas Raiders | Chargers -3, O/U 44.5 | Chargers win 20-9 |
| 3 | Detroit Lions vs. Baltimore Ravens | Ravens -3.5, O/U 49.5 | Lions win 38-30 |
| 4 | New York Jets vs. Miami Dolphins | Dolphins -5.5, O/U 44.5 | Dolphins win 27-21 |
| 4 | Cincinnati Bengals vs. Denver Broncos | Broncos -2.5, O/U 47.5 | Broncos win 28-3 |
| 5 | Kansas City Chiefs vs. Jacksonville Jaguars | Chiefs -4.5, O/U 47.5 | Jaguars win 31-28 |
| 6 | Buffalo Bills vs. Atlanta Falcons | Bills -5.5, O/U 48.5 | Falcons win 24-14 |
| 6 | Chicago Bears vs, Washington Commanders | Commanders -4.5, O/U 48.5 | Bears win 25-24 |
| 7 | Tampa Bay Buccaneers vs. Detroit Lions | Lions -3.5, O/U 49.5 | Lions win 24-9 |
| 7 | Houston Texans vs. Seattle Seahawks | Seahawks -1.5, O/U 44.5 | Seahawks win 27-19 |
| 8 | Washington Commanders vs. Kansas City Chiefs | Chiefs -3.5, O/U 48.5 | Chiefs win 28-7 |
| 9 | Arizona Cardinals vs. Dallas Cowboys | Cowboys -2.5, O/U 54.5 | Cardinals win 27-17 |
| 10 | Philadelphia Eagles vs. Green Bay Packers | Eagles -1.5, O/U 45.5 | Eagles win 10-7 |
| 11 | Dallas Cowboys vs. Las Vegas Raiders | Cowboys -1.5, O/U 45.5 | Cowboys win 33-16 |
| 12 | Carolina Panthers vs. San Francisco 49ers | 49ers -7, O/U 46.5 | 49ers won 20-9 |
| 13 | New York Giants vs. New England Patriots | Patriots -7.5, O/U 46.5 | Patriots win 33-15 |
| 14 | Philadelphia Eagles vs. Los Angeles Chargers | Eagles -2.5, O/U 40.5 | Chargers win 22-19 (OT) |
| 15 | Miami Dolphins vs. Pittsburgh Steelers | Steelers -3, O/U 42.5 | Steelers win 28-15 |
| 16 | San Francisco 49ers vs. Indianapolis Colts | 49ers -6.5, O/U 46.5 | 49ers win 48-27 |
| 17 | Los Angeles Rams vs. Atlanta Falcons | Rams -7.5, O/U 49.5 | ESPN |
Best MNF Matchups Based On Betting Odds
Week 16: San Francisco 49ers @ Indianapolis Colts
This matchup is compelling because it pits star power against resilience on both sides of the ball, starting with Brock Purdyâs efficiency and poise leading a 49ers offense that thrives on balance and timing. San Francisco will lean heavily on George Kittleâs ability to dominate the middle of the field. Still, the Coltsâ defenseâphysical, disciplined, and opportunisticâhas shown it can disrupt elite offenses when it controls the line of scrimmage. On the other side, Jonathan Taylor remains the engine of Indianapolisâ offense. He presents a massive challenge for a young 49ers defense that has been inconsistent without stars Nick Bosa and Fred Warner. Stopping Taylor will be the defining test for San Franciscoâs next wave of defenders. At the same time, Indianapolis looks to shorten the game and protect Philip Rivers by leaning on its ground attack. With contrasting styles, emerging talent, and high stakes for both teams, this game has all the ingredients for a tense, high-quality showdown.
Worst MNF Matchups Based On Betting Odds
Week 17: Los Angeles Rams vs. Atlanta Falcons
The Week 17 Monday Night Football matchup between the Rams and Falcons has the makings of a lopsided affair, as Los Angeles enters as the clearly superior team on both sides of the ball. While the Rams are playing like one of the leagueâs top teams and surging at the right time, Atlanta has often looked lifeless, struggling to find consistency and urgency as the season winds down. That imbalance could become glaring if the Falcons fail to get Bijan Robinson going early, as their offense tends to stall when the running game is neutralized. If the Rams jump out to an early lead and force Atlanta to play from behind, this primetime game could quickly get out of hand, making it a less-than-ideal showcase for Monday Night Football.
How To Bet On Monday Night Football Odds
There are a variety of different types of bets that bettors can make on Monday Night Football, from moneyline wagers to prop bets to spread to over/unders. A moneyline wager is the simplest form, which is just a bet on which team will win the game. Check your favorite online sportsbook to see all the betting options available.
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Monday Night Football Live Betting
The great thing about live betting a Monday Night Football game is that there is always an opportunity to get in on the action. The more time that passes in a MNF game, the more information you have as a bettor about how the rest of the game could potentially play out. While you may pay more of a vig with an in-game wager, it's well worth it to make those wagers -- especially if there are weather concerns or a player gets injured that isn't fully reflected in the odds.
Bet the MNF Moneyline
The moneyline wager is the simplest wager that you can make on a Monday Night Football game when betting, as you're simply picking the team to win the game. For the team that is favored, you'll win less money (because they're expected to win), but there can be good money to be made on betting a underdog to win outright at a plus-money price.
Bet the MNF Spread
Oddsmakers assign point spreads to each team in a game, which allows bettors the ability to wager on the final outcome -- not just which team wins or loses, but by how much. For example, if the Chiefs are 8-point favorites against the Saints, Kansas City needs to win by 9 points or more to cover the spread. If the Chiefs won 27-20, they would have won on the moneyline, but not covered the spread in that game.
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Historical MNF Betting Trends
Just like Thursday Night Football is unique, Monday Night Football is a different handicapping process for bettors. The players will have an extra day of rest and preparation heading into the game, and that can mitigate the impact of travel as well.
MNF Betting Tips
There are a lot of important betting tips to remember before wagering on a MNF game, and it's vital to remember that it's different than a normal game. Some players or coaches are better in primetime than others, there is more time to recover from injuries and always consider what point during the season the game is being played.
Do research
Monday Night Football is a different handicap from the rest of the week's games. Bettors need to know when/where teams played the prior week, if there are injuries, the team is coming off a bye, etc.
Check the injury report
Unlike Thursday Night Football where an injury to a player the previous Sunday may result in him not playing, players have extra time to recover for a MNF game. Be sure to check the injury report consistently to see how important players are progressing throughout the week.
Consider when the game is being played
Late in the season, some teams have more motivation to win than others. And in regards to betting, teams are certainly not going to care about covering the spread. A Week 16 matchup between the Saints and Packers (-5) may not matter if Green Bay is running away with the division or vice-versa if the Saints have clinched the NFC South and can't improve seeding. Always be sure to know what's at stake for both teams later in the season.
How To Watch Monday Night Football in 2025
Most Monday Night Football games this season will be played at 8:15 p.m. ET on ESPN. You can watch from any streaming device or a TV that has ESPN in its cable bundle. Joe Buck and Troy Aikman will be announcing every game.
Final Word on 2025 MNF Odds
The NFL season is right around the corner and that means Monday Night Football is here! With 39 states now having legalized sports betting, it's easier than every to bet the moneyline, spread or wager live during a game. There are a ton of exciting MNF matchups this season to watch!
đ More NFL:
- Thursday Night Fooball Odds
- Sunday Night Football Odds
- Detroit Lions Betting Odds Guide
- Detroit Lions Playoff Chances
- Detroit Lions Super Bowl Odds
Monday Night Football Odds FAQ
The Los Angeles Rams are currently 7.5-point favorites in their matchup with the Atlanta Falcons this week on Monday Night Football, with the game taking place at Mercedes-Benz Stadium in Atlanta, Georgia. The Rams are attempting to stay alive for the top seed in the NFC, while the Falcons are eliminated.
You can bet on Monday Night Football at any brick-and-mortar casino in a state with legalized sports betting or on your phone by signing up for an online sportsbook in one of the 39 states where sports betting is legal.
Yes. Several teams will play on Monday Night Football twice this season, including the Dallas Cowboys, Philadelphia Eagles, Tampa Bay Buccaneers, Atlanta Falcons, Los Angeles Chargers, Las Vegas Raiders, Detroit Lions, Miami Dolphins, Kansas City Chiefs, Washington Commanders, and Houston Texans.
Home teams are currently 11-9 this season on Monday Night Football. When the season began, it was a strange stretch where the away teams won four in a row, and now they have won three games in a row after a brief stretch.
You can watch Monday Night Football on any television, phone, or streaming device with ESPN, ABC, or cable if you are subscribed to ESPN. Local games can often be seen on ABC, so it's always best to check your local listings.
Week 10 was the most exciting and thrilling Monday Night Football matchup of the year, when the Philadelphia Eagles traveled to Lambeau Field to battle the Green Bay Packers in a rematch of the NFC Wildcard showdown from last season.
Author

Ben Fawkes is a Las Vegas-based sports betting expert insider, journalist, and analyst. Ben has been in the sports industry since 2010, overseeing digital content for ESPN and VSiN and shaping strategy for popular sports betting TV shows such as ESPN's Daily Wager, along with other VSiN shows, podcasts, and YouTube content.